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Yibin Wang, Ph.D.

   
Vice-Chair, Research and Professor, Anesthesiology
Professor, Medicine
Member, California NanoSystems Institute, Cell & Developmental Biology GPB Home Area, Center for Duchenne Muscular Dystrophy, Genetics & Genomics GPB Home Area, JCCC Signal Transduction and Therapeutics Program Area, Molecular, Cellular & Integrative Physiology GPB Home Area, themes
Faculty, Cardiovascular Research Laboratory, Cardiology

Education:
Degrees:
Ph.D., Baylor College of Medicine, 1993
B.S., New York State University, 1988 -

Contact Information:
Work Email Address: yibinwang@mednet.ucla.edu
Work Email Address: ywangibi@ucla.edu
Mailing Address: Laboratory
UCLA, David Geffen School of Medicine
Department of Anesthesiology
Division of Molecular Medicine
650 Charles E Young Dr.
CHS/BH569
Los Angeles, CA 90095
UNITED STATES
Work Address: Office
CHS BH-569
Campus - 711520
CA
UNITED STATES
Home Page: https://www.anes.ucla.edu/dmm/wang/
Work Phone Number: (310)2065197

Selected Publications:

Touma Marlin, Reemtsen Brian, Halnon Nancy, Alejos Juan, Finn J Paul, Nelson Stanley F, Wang Yibin, A Path to Implement Precision Child Health Cardiovascular Medicine, Frontiers in cardiovascular medicine, 2017, 4 (4), 36.
Rose Beth A, Yokota Tomohiro, Chintalgattu Vishnu, Ren Shuxun, Iruela-Arispe Luisa, Khakoo Aarif Y, Minamisawa Susumu, Wang Yibin, Cardiac Myocyte p38α Kinase Regulates Angiogenesis via Myocyte-Endothelial Cell Cross-talk During Stress-Induced Remodeling in Heart, The Journal of biological chemistry, 2017, 21 (4), 817-827.
Gao Chen, Howard-Quijano Kimberly, Rau Christoph, Takamiya Tatsuo, Song Yang, Shivkumar Kalyanam, Wang Yibin, Mahajan Aman, Inflammatory and apoptotic remodeling in autonomic nervous system following myocardial infarction, PloS one, 2017, 12 (5), e0177750.
Seldin Marcus M, Kim Eric D, Romay Milagros C, Li Shen, Rau Christoph D, Wang Jessica J, Krishnan Karthickeyan Chella, Wang Yibin, Deb Arjun, Lusis Aldons J, A systems genetics approach identifies Trp53inp2 as a link between cardiomyocyte glucose utilization and hypertrophic response, American journal of physiology. Heart and circulatory physiology, 2017, 312 (4), H728-H741.
Cong Qian, Jia Hao, Li Ping, Qiu Shoutao, Yeh James, Wang Yibin, Zhang Zhen-Lin, Ao Junping, Li Baojie, Liu Huijuan, p38α MAPK regulates proliferation and differentiation of osteoclast progenitors and bone remodeling in an aging-dependent manner, Scientific reports, 2017, 7 (5), 45964.
Pillai Indulekha C L, Li Shen, Romay Milagros, Lam Larry, Lu Yan, Huang Jie, Dillard Nathaniel, Zemanova Marketa, Rubbi Liudmilla, Wang Yibin, Lee Jason, Xia Ming, Liang Owen, Xie Ya-Hong, Pellegrini Matteo, Lusis Aldons J, Deb Arjun, Cardiac Fibroblasts Adopt Osteogenic Fates and Can Be Targeted to Attenuate Pathological Heart Calcification, Cell stem cell, 2017, 20 (2), 218-232.e5.
Ding Yichen, Lee Juhyun, Ma Jianguo, Sung Kevin, Yokota Tomohiro, Singh Neha, Dooraghi Mojdeh, Abiri Parinaz, Wang Yibin, Kulkarni Rajan P, Nakano Atsushi, Nguyen Thao P, Fei Peng, Hsiai Tzung K, Light-sheet fluorescence imaging to localize cardiac lineage and protein distribution, Scientific reports, 2017, 7 (3), 42209.
Rau Christoph D, Romay Milagros C, Tuteryan Mary, Wang Jessica J-C, Santolini Marc, Ren Shuxun, Karma Alain, Weiss James N, Wang Yibin, Lusis Aldons J, Systems Genetics Approach Identifies Gene Pathways and Adamts2 as Drivers of Isoproterenol-Induced Cardiac Hypertrophy and Cardiomyopathy in Mice, Cell systems, 2017, 4 (1), 121-128.e4.
Touma, M.; Kang, X.; Zhao, Y.; Cass, A. A.; Gao, F.; Biniwale, R.; Coppola, G.; Xiao, X.; Reemtsen, B.; Wang, Y., Decoding the Long Noncoding RNA During Cardiac Maturation: A Roadmap for Functional Discovery, Circ Cardiovasc Genet, 2016, 9 (5), 395-407.
Wang, J. J.; Rau, C.; Avetisyan, R.; Ren, S.; Romay, M. C.; Stolin, G.; Gong, K. W.; Wang, Y.; Lusis, A. J., Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model, PLoS Genet, 2016, 12 (7), e1006038.
Gao, C.; Wang, Y., Positive Role for a Negative Calcineurin Regulator in Cardiac Hypertrophy, Hypertension, 2016, 67 (5), 841-2.
Gao, C.; Ren, S.; Lee, J. H.; Qiu, J.; Chapski, D. J.; Rau, C. D.; Zhou, Y.; Abdellatif, M.; Nakano, A.; Vondriska, T. M.; Xiao, X.; Fu, X. D.; Chen, J. N.; Wang, Y., RBFox1-mediated RNA splicing regulates cardiac hypertrophy and heart failure, J Clin Invest, 2016, 126 (1), 195-206.
Lusis, A. J.; Seldin, M. M.; Allayee, H.; Bennett, B. J.; Civelek, M.; Davis, R. C.; Eskin, E.; Farber, C. R.; Hui, S.; Mehrabian, M.; Norheim, F.; Pan, C.; Parks, B.; Rau, C. D.; Smith, D. J.; Vallim, T.; Wang, Y.; Wang, J., The Hybrid Mouse Diversity Panel: a resource for systems genetics analyses of metabolic and cardiovascular traits, J Lipid Res, 2016, 57 (6), 925-42.
Wang, Z.; Zhang, X. J.; Ji, Y. X.; Zhang, P.; Deng, K. Q.; Gong, J.; Ren, S.; Wang, X.; Chen, I.; Wang, H.; Gao, C.; Yokota, T.; Ang, Y. S.; Li, S.; Cass, A.; Vondriska, T. M.; Li, G.; Deb, A.; Srivastava, D.; Yang, H. T.; Xiao, X.; Li, H.; Wang, Y., The long noncoding RNA Chaer defines an epigenetic checkpoint in cardiac hypertrophy, Nat Med, 2016, 22 (10), 1131-1139.
Sun Haipeng, Wang Yibin, Branched chain amino acid metabolic reprogramming in heart failure, Biochimica et biophysica acta, 2016, 1862 (12), 2270-2275.
Dong Weibing, Zhou Meiyi, Dong Mei, Pan Bangfen, Liu Yunxia, Shao Jing, Gu Xiaoping, Huang Ying, Li Guangping, Wang Yibin, Sun Haipeng, Keto acid metabolites of branched-chain amino acids inhibit oxidative stress-induced necrosis and attenuate myocardial ischemia-reperfusion injury, Journal of molecular and cellular cardiology, 2016, 101 (12), 90-98.
Rau, C. D.; Romay, M. C.; Tuteryan, M.; Wang, J. J.; Santolini, M.; Ren, S.; Karma, A.; Weiss, J. N.; Wang, Y.; Lusis, A. J., Systems Genetics Approach Identifies Gene Pathways and Adamts2 as Drivers of Isoproterenol-Induced Cardiac Hypertrophy and Cardiomyopathy in Mice, Cell Syst, 2016.
Pillai, I. C.; Li, S.; Romay, M.; Lam, L.; Lu, Y.; Huang, J.; Dillard, N.; Zemanova, M.; Rubbi, L.; Wang, Y.; Lee, J.; Xia, M.; Liang, O.; Xie, Y. H.; Pellegrini, M.; Lusis, A. J.; Deb, A., Cardiac Fibroblasts Adopt Osteogenic Fates and Can Be Targeted to Attenuate Pathological Heart Calcification, Cell Stem Cell, 2016.
Dong, W.; Zhou, M.; Dong, M.; Pan, B.; Liu, Y.; Shao, J.; Gu, X.; Huang, Y.; Li, G.; Wang, Y.; Sun, H., Keto acid metabolites of branched-chain amino acids inhibit oxidative stress-induced necrosis and attenuate myocardial ischemia-reperfusion injury, J Mol Cell Cardiol, 2016, 101, 90-98.
Franklin Sarah, Kimball Todd, Rasmussen Tara L, Rosa-Garrido Manuel, Chen Haodong, Tran Tam, Miller Mickey R, Gray Ricardo, Jiang Shanxi, Ren Shuxun, Wang Yibin, Tucker Haley O, Vondriska Thomas M, The chromatin-binding protein Smyd1 restricts adult mammalian heart growth, American journal of physiology. Heart and circulatory physiology, 2016, 311 (5), H1234-H1247.
Franklin, S.; Kimball, T.; Rasmussen, T. L.; Rosa-Garrido, M.; Chen, H.; Tran, T.; Miller, M. R.; Gray, R.; Jiang, S.; Ren, S.; Wang, Y.; Tucker, H. O.; Vondriska, T. M., The chromatin-binding protein Smyd1 restricts adult mammalian heart growth, Am J Physiol Heart Circ Physiol, 2016, 311 (5), H1234-H1247.
Wang, J. J.; Aboulhosn, J. A.; Hofer, I. S.; Mahajan, A.; Wang, Y.; Vondriska, T. M., Operationalizing Precision Cardiovascular Medicine: Three Innovations, Circ Res, 2016, 119 (9), 984-987.
Touma Marlin, Kang Xuedong, Zhao Yan, Cass Ashley A, Gao Fuying, Biniwale Reshma, Coppola Giovanni, Xiao Xinshu, Reemtsen Brian, Wang Yibin, Decoding the Long Noncoding RNA During Cardiac Maturation: A Roadmap for Functional Discovery, Circulation. Cardiovascular genetics, 2016, 9 (5), 395-407.
Wang Jessica J, Aboulhosn Jamil A, Hofer Ira S, Mahajan Aman, Wang Yibin, Vondriska Thomas M, Operationalizing Precision Cardiovascular Medicine: Three Innovations, Circulation research, 2016, 119 (9), 984-987.
Wang Zhihua, Zhang Xiao-Jing, Ji Yan-Xiao, Zhang Peng, Deng Ke-Qiong, Gong Jun, Ren Shuxun, Wang Xinghua, Chen Iris, Wang He, Gao Chen, Yokota Tomohiro, Ang Yen Sin, Li Shen, Cass Ashley, Vondriska Thomas M, Li Guangping, Deb Arjun, Srivastava Deepak, Yang Huang-Tian, Xiao Xinshu, Li Hongliang, Wang Yibin, The long noncoding RNA Chaer defines an epigenetic checkpoint in cardiac hypertrophy, Nature medicine, 2016, 22 (10), 1131-1139.
Rau, C. D.; Gao, C.; Wang, Y., Deconvolution of the Human Endothelial Transcriptome, Cell Syst, 2016, 3 (3), 218-220.
Sun, H.; Wang, Y., Branched chain amino acid metabolic reprogramming in heart failure, Biochim Biophys Acta, 2016.
Rau Christoph D, Gao Chen, Wang Yibin, Deconvolution of the Human Endothelial Transcriptome, Cell systems, 2016, 3 (3), 218-220.
Karbassi Elaheh, Monte Emma, Chapski Douglas J, Lopez Rachel, Rosa Garrido Manuel, Kim Joseph, Wisniewski Nicholas, Rau Christoph D, Wang Jessica J, Weiss James N, Wang Yibin, Lusis Aldons J, Vondriska Thomas M, Relationship of disease-associated gene expression to cardiac phenotype is buffered by genetic diversity and chromatin regulation, Physiological genomics, 2016, 48 (8), 601-15.
Karbassi, E.; Monte, E.; Chapski, D. J.; Lopez, R.; Rosa Garrido, M.; Kim, J.; Wisniewski, N.; Rau, C. D.; Wang, J. J.; Weiss, J. N.; Wang, Y.; Lusis, A. J.; Vondriska, T. M., Relationship of disease-associated gene expression to cardiac phenotype is buffered by genetic diversity and chromatin regulation, Physiol Genomics, 2016, 48 (8), 601-15.
Monte, E.; Rosa-Garrido, M.; Karbassi, E.; Chen, H.; Lopez, R.; Rau, C. D.; Wang, J.; Nelson, S. F.; Wu, Y.; Stefani, E.; Lusis, A. J.; Wang, Y.; Kurdistani, S. K.; Franklin, S.; Vondriska, T. M., Reciprocal Regulation of the Cardiac Epigenome by Chromatin Structural Proteins Hmgb and Ctcf: IMPLICATIONS FOR TRANSCRIPTIONAL REGULATION, J Biol Chem, 2016, 291 (30), 15428-46.
Wang Jessica Jen-Chu, Rau Christoph, Avetisyan Rozeta, Ren Shuxun, Romay Milagros C, Stolin Gabriel, Gong Ke Wei, Wang Yibin, Lusis Aldons J, Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model, PLoS genetics, 2016, 12 (7), e1006038.
Monte Emma, Rosa-Garrido Manuel, Karbassi Elaheh, Chen Haodong, Lopez Rachel, Rau Christoph D, Wang Jessica, Nelson Stanley F, Wu Yong, Stefani Enrico, Lusis Aldons J, Wang Yibin, Kurdistani Siavash K, Franklin Sarah, Vondriska Thomas M, Reciprocal Regulation of the Cardiac Epigenome by Chromatin Structural Proteins Hmgb and Ctcf: IMPLICATIONS FOR TRANSCRIPTIONAL REGULATION, The Journal of biological chemistry, 2016, 291 (30), 15428-46.
Lusis Aldons J, Seldin Marcus M, Allayee Hooman, Bennett Brian J, Civelek Mete, Davis Richard C, Eskin Eleazar, Farber Charles R, Hui Simon, Mehrabian Margarete, Norheim Frode, Pan Calvin, Parks Brian, Rau Christoph D, Smith Desmond J, Vallim Thomas, Wang Yibin, Wang Jessica, The Hybrid Mouse Diversity Panel: a resource for systems genetics analyses of metabolic and cardiovascular traits, Journal of lipid research, 2016, 57 (6), 925-42.
Sun, H.; Olson, K. C.; Gao, C.; Prosdocimo, D. A.; Zhou, M.; Wang, Z.; Jeyaraj, D.; Youn, J. Y.; Ren, S.; Liu, Y.; Rau, C. D.; Shah, S.; Ilkayeva, O.; Gui, W. J.; William, N. S.; Wynn, R. M.; Newgard, C. B.; Cai, H.; Xiao, X.; Chuang, D. T.; Schulze, P. C.; Lynch, C.; Jain, M. K.; Wang, Y., Catabolic Defect of Branched-Chain Amino Acids Promotes Heart Failure, Circulation, 2016, 133 (21), 2038-49.
Sun Haipeng, Olson Kristine C, Gao Chen, Prosdocimo Domenick A, Zhou Meiyi, Wang Zhihua, Jeyaraj Darwin, Youn Ji-Youn, Ren Shuxun, Liu Yunxia, Rau Christoph D, Shah Svati, Ilkayeva Olga, Gui Wen-Jun, William Noelle S, Wynn R Max, Newgard Christopher B, Cai Hua, Xiao Xinshu, Chuang David T, Schulze Paul Christian, Lynch Christopher, Jain Mukesh K, Wang Yibin, Catabolic Defect of Branched-Chain Amino Acids Promotes Heart Failure, Circulation, 2016, 133 (21), 2038-49.
Gao Chen, Wang Yibin, Positive Role for a Negative Calcineurin Regulator in Cardiac Hypertrophy, Hypertension (Dallas, Tex. : 1979), 2016, 67 (5), 841-2.
Cong, Q.; Jia, H.; Biswas, S.; Li, P.; Qiu, S.; Deng, Q.; Guo, X.; Ma, G.; Ling Chau, J. F.; Wang, Y.; Zhang, Z. L.; Jiang, X.; Liu, H.; Li, B., p38alpha MAPK Regulates Lineage Commitment and OPG Synthesis of Bone Marrow Stromal Cells to Prevent Bone Loss under Physiological and Pathological Conditions, Stem Cell Reports, 2016, 6 (4), 566-78.
Chen, H.; Orozco, L. D.; Wang, J.; Rau, C. D.; Rubbi, L.; Ren, S.; Wang, Y.; Pellegrini, M.; Lusis, A. J.; Vondriska, T. M., DNA Methylation Indicates Susceptibility to Isoproterenol-Induced Cardiac Pathology and Is Associated With Chromatin States, Circ Res, 2016, 118 (5), 786-97.
Chen Haodong, Orozco Luz D, Wang Jessica, Rau Christoph D, Rubbi Liudmilla, Ren Shuxun, Wang Yibin, Pellegrini Matteo, Lusis Aldons J, Vondriska Thomas M, DNA Methylation Indicates Susceptibility to Isoproterenol-Induced Cardiac Pathology and Is Associated With Chromatin States, Circulation research, 2016, 118 (5), 786-97.
Iorga, A.; Li, J.; Sharma, S.; Umar, S.; Bopassa, J. C.; Nadadur, R. D.; Centala, A.; Ren, S.; Saito, T.; Toro, L.; Wang, Y.; Stefani, E.; Eghbali, M., Rescue of Pressure Overload-Induced Heart Failure by Estrogen Therapy, J Am Heart Assoc, 2016, 5 (1).
Yokota, Tomohiro; Wang, Yibin, p38 MAP kinases in the heart, Gene, 2016, 575 (2), 369-376.
Gao Chen, Ren Shuxun, Lee Jae-Hyung, Qiu Jinsong, Chapski Douglas J, Rau Christoph D, Zhou Yu, Abdellatif Maha, Nakano Astushi, Vondriska Thomas M, Xiao Xinshu, Fu Xiang-Dong, Chen Jau-Nian, Wang Yibin, RBFox1-mediated RNA splicing regulates cardiac hypertrophy and heart failure, The Journal of clinical investigation, 2016, 126 (1), 195-206.
Iorga Andrea, Li Jingyuan, Sharma Salil, Umar Soban, Bopassa Jean C, Nadadur Rangarajan D, Centala Alexander, Ren Shuxun, Saito Tomoaki, Toro Ligia, Wang Yibin, Stefani Enrico, Eghbali Mansoureh, Rescue of Pressure Overload-Induced Heart Failure by Estrogen Therapy, Journal of the American Heart Association, 2016, 5 (1), 361-6.
Yokota Tomohiro, Wang Yibin, p38 MAP kinases in the heart, Gene, 2016, 575 (2 Pt 2), 369-76.
Song, Y.; Zhang, Y.; Jiang, H.; Zhu, Y.; Liu, L.; Feng, W.; Yang, L.; Wang, Y.; Li, M., Activation of Notch3 promotes pulmonary arterial smooth muscle cells proliferation via Hes1/p27Kip1 signaling pathway, FEBS Open Bio, 2015, 5, 656-60.
Rau, C. D.; Lusis, A. J.; Wang, Y., Genetics of common forms of heart failure: challenges and potential solutions, Curr Opin Cardiol, 2015, 30 (3), 222-7.
Rau, C. D.; Parks, B.; Wang, Y.; Eskin, E.; Simecek, P.; Churchill, G. A.; Lusis, A. J., High-Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping, G3 (Bethesda), 2015, 5 (10), 2021-6.
Cai, R.; Gu, J.; Sun, H.; Liu, X.; Mei, W.; Qi, Y.; Xue, S.; Ren, S.; Rabinowitz, J. E.; Wang, Y.; Yeh, E. T.; Cheng, J., Induction of SENP1 in myocardium contributes to abnormities of mitochondria and cardiomyopathy, J Mol Cell Cardiol, 2015, 79, 115-22.
Feng, J.; Gong, D.; Fu, X.; Wu, T. T.; Wang, J.; Chang, J.; Zhou, J.; Lu, G.; Wang, Y.; Sun, R., M1 of Murine Gamma-Herpesvirus 68 Induces Endoplasmic Reticulum Chaperone Production, Sci Rep, 2015, 5, 17228.
Rau, C. D.; Wang, J.; Avetisyan, R.; Romay, M. C.; Martin, L.; Ren, S.; Wang, Y.; Lusis, A. J., Mapping genetic contributions to cardiac pathology induced by Beta-adrenergic stimulation in mice, Circ Cardiovasc Genet, 2015, 8 (1), 40-9.
Neelankavil, J.; Rau, C. D.; Wang, Y., The Genetic Basis of Coronary Artery Disease and Atrial Fibrillation: A Search for Disease Mechanisms and Therapeutic Targets, J Cardiothorac Vasc Anesth, 2015, 29 (5), 1328-32.
Sun, H.; Wang, Y., The elusive philosopher's stone in young blood, Circ Res, 2015, 117 (11), 906-8.
Feng Jiaying, Gong Danyang, Fu Xudong, Wu Ting-ting, Wang Jane, Chang Jennifer, Zhou Jingting, Lu Gang, Wang Yibin, Sun Ren, M1 of Murine Gamma-Herpesvirus 68 Induces Endoplasmic Reticulum Chaperone Production, Scientific reports, 2015, 5 (52), 17228.
Cattin, M. E.; Wang, J.; Weldrick, J. J.; Roeske, C. L.; Mak, E.; Thorn, S. L.; DaSilva, J. N.; Wang, Y.; Lusis, A. J.; Burgon, P. G., Deletion of MLIP (Muscle-enriched A-type Lamin-interacting Protein) Leads to Cardiac Hyperactivation of Akt/Mammalian Target of Rapamycin (mTOR) and Impaired Cardiac Adaptation, J Biol Chem, 2015, 290 (44), 26699-714.
Sun, H.; Gao, C.; Wang, Y., A H(a)rd Way to Adapt in Cardiac Hypertrophy, Circ Res, 2015, 117 (6), 484-6.
Deb, A.; Wang, Y., Hypertrophic preconditioning: short-term tricks for long-term gain, Circulation, 2015, 131 (17), 1468-70.
Wang, Z.; Wang, Y., Dawn of the Epi-LncRNAs: new path from Myheart, Circ Res, 2015, 116 (2), 235-6.
Ren, S.; Lu, G.; Ota, A.; Zhou, Z. H.; Vondriska, T. M.; Lane, T. F.; Wang, Y., IRE1 phosphatase PP2Ce regulates adaptive ER stress response in the postpartum mammary gland, PLoS One, 2014, 9 (11), e111606.
Sun, H.; Wang, Y., Interferon regulatory factors in heart: stress response beyond inflammation, Hypertension, 2014, 63 (4), 663-4.
Lam, M. P.; Wang, D.; Lau, E.; Liem, D. A.; Kim, A. K.; Ng, D. C.; Liang, X.; Bleakley, B. J.; Liu, C.; Tabaraki, J. D.; Cadeiras, M.; Wang, Y.; Deng, M. C.; Ping, P., Protein kinetic signatures of the remodeling heart following isoproterenol stimulation, J Clin Invest, 2014, 124 (4), 1734-44.
Gao, C.; Wang, Y., Transcriptome complexity in cardiac development and diseases--an expanding universe between genome and phenome, Circ J, 2014, 78 (5), 1038-47.
Briot, A.; Jaroszewicz, A.; Warren, C. M.; Lu, J.; Touma, M.; Rudat, C.; Hofmann, J. J.; Airik, R.; Weinmaster, G.; Lyons, K.; Wang, Y.; Kispert, A.; Pellegrini, M.; Iruela-Arispe, M. L., Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells, Dev Cell, 2014, 31 (6), 707-21.
Wang, Y., Blind dates in sciences: dealing with rejection in peer review, Circ Res, 2014, 114 (6), 944-6.
Xiao, X. G.; Touma, M.; Wang, Y., Decoding the noncoding transcripts in human heart failure, Circulation, 2014, 129 (9), 958-60.
Gupta, A.; Rohlfsen, C.; Leppo, M. K.; Chacko, V. P.; Wang, Y.; Steenbergen, C.; Weiss, R. G., Creatine kinase-overexpression improves myocardial energetics, contractile dysfunction and survival in murine doxorubicin cardiotoxicity, PLoS One, 2013, 8 (10), e74675.
Foster, W. H.; Langenbacher, A.; Gao, C.; Chen, J.; Wang, Y., Nuclear phosphatase PPM1G in cellular survival and neural development, Dev Dyn, 2013, 242 (9), 1101-9.
Lu, G.; Ota, A.; Ren, S.; Franklin, S.; Rau, C. D.; Ping, P.; Lane, T. F.; Zhou, Z. H.; Reue, K.; Lusis, A. J.; Vondriska, T.; Wang, Y., PPM1l encodes an inositol requiring-protein 1 (IRE1) specific phosphatase that regulates the functional outcome of the ER stress response, Mol Metab, 2013, 2 (4), 405-16.
Monte, E.; Mouillesseaux, K.; Chen, H.; Kimball, T.; Ren, S.; Wang, Y.; Chen, J. N.; Vondriska, T. M.; Franklin, S., Systems proteomics of cardiac chromatin identifies nucleolin as a regulator of growth and cellular plasticity in cardiomyocytes, Am J Physiol Heart Circ Physiol, 2013, 305 (11), H1624-38.
Force, T.; Wang, Y., Mechanism-based engineering against anthracycline cardiotoxicity, Circulation, 2013, 128 (2), 98-100.
Ahuja, P.; Wanagat, J.; Wang, Z.; Wang, Y.; Liem, D. A.; Ping, P.; Antoshechkin, I. A.; Margulies, K. B.; Maclellan, W. R., Divergent mitochondrial biogenesis responses in human cardiomyopathy, Circulation, 2013, 127 (19), 1957-67.
Li, J.; Umar, S.; Iorga, A.; Youn, J. Y.; Wang, Y.; Regitz-Zagrosek, V.; Cai, H.; Eghbali, M., Cardiac vulnerability to ischemia/reperfusion injury drastically increases in late pregnancy, Basic Res Cardiol, 2012, 107 (4), 271.
Gao, C.; Wang, Y., Global impact of RNA splicing on transcriptome remodeling in the heart, J Zhejiang Univ Sci B, 2012, 13 (8), 603-8.
Ghazalpour, A.; Rau, C. D.; Farber, C. R.; Bennett, B. J.; Orozco, L. D.; van Nas, A.; Pan, C.; Allayee, H.; Beaven, S. W.; Civelek, M.; Davis, R. C.; Drake, T. A.; Friedman, R. A.; Furlotte, N.; Hui, S. T.; Jentsch, J. D.; Kostem, E.; Kang, H. M.; Kang, E. Y.; Joo, J. W.; Korshunov, V. A.; Laughlin, R. E.; Martin, L. J.; Ohmen, J. D.; Parks, B. W.; Pellegrini, M.; Reue, K.; Smith, D. J.; Tetradis, S.; Wang, J.; Wang, Y.; Weiss, J. N.; Kirchgessner, T.; Gargalovic, P. S.; Eskin, E.; Lusis, A. J.; LeBoeuf, R. C., Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits, Mamm Genome, 2012, 23 (9-10), 680-92.
Sun, H.; Wang, Y., Novel Ser/Thr protein phosphatases in cell death regulation, Physiology (Bethesda), 2012, 27 (1), 43-52.
Franklin, S.; Chen, H.; Mitchell-Jordan, S.; Ren, S.; Wang, Y.; Vondriska, T. M., Quantitative analysis of the chromatin proteome in disease reveals remodeling principles and identifies high mobility group protein B2 as a regulator of hypertrophic growth, Mol Cell Proteomics, 2012, 11 (6), M111 014258.
MacLellan, W. R.; Wang, Y.; Lusis, A. J., Systems-based approaches to cardiovascular disease, Nat Rev Cardiol, 2012, 9 (3), 172-84.
Foster, W. H.; Tidball, J. G.; Wang, Y., p38gamma activity is required for maintenance of slow skeletal muscle size, Muscle Nerve, 2012, 45 (2), 266-73.
Hofmann, J. J.; Briot, A.; Enciso, J.; Zovein, A. C.; Ren, S.; Zhang, Z. W.; Radtke, F.; Simons, M.; Wang, Y.; Iruela-Arispe, M. L., Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome, Development, 2012, 139 (23), 4449-60.
Hajjar, R. J.; Leri, A.; Wang, Y., BCVS scientific conference 2012 meeting report, Circ Res, 2012, 111 (9), 1121-4.
Akki, A.; Su, J.; Yano, T.; Gupta, A.; Wang, Y.; Leppo, M. K.; Chacko, V. P.; Steenbergen, C.; Weiss, R. G., Creatine kinase overexpression improves ATP kinetics and contractile function in postischemic myocardium, Am J Physiol Heart Circ Physiol, 2012, 303 (7), H844-52.
Weiss, J. N.; Karma, A.; MacLellan, W. R.; Deng, M.; Rau, C. D.; Rees, C. M.; Wang, J.; Wisniewski, N.; Eskin, E.; Horvath, S.; Qu, Z.; Wang, Y.; Lusis, A. J., "Good enough solutions" and the genetics of complex diseases, Circ Res, 2012, 111 (4), 493-504.
Zhou, M.; Lu, G.; Gao, C.; Wang, Y.; Sun, H., Tissue-specific and nutrient regulation of the branched-chain alpha-keto acid dehydrogenase phosphatase, protein phosphatase 2Cm (PP2Cm), J Biol Chem, 2012, 287 (28), 23397-406.
Sun, H.; Wang, Y., Prostaglandin E2 in remote control of myocardial remodeling, Circulation, 2012, 125 (23), 2818-20.
Jeyaraj, D.; Scheer, F. A.; Ripperger, J. A.; Haldar, S. M.; Lu, Y.; Prosdocimo, D. A.; Eapen, S. J.; Eapen, B. L.; Cui, Y.; Mahabeleshwar, G. H.; Lee, H. G.; Smith, M. A.; Casadesus, G.; Mintz, E. M.; Sun, H.; Wang, Y.; Ramsey, K. M.; Bass, J.; Shea, S. A.; Albrecht, U.; Jain, M. K., Klf15 orchestrates circadian nitrogen homeostasis, Cell Metab, 2012, 15 (3), 311-23.
Ota, A.; Wang, Y., Cdc37/Hsp90 protein-mediated regulation of IRE1alpha protein activity in endoplasmic reticulum stress response and insulin synthesis in INS-1 cells, J Biol Chem, 2012, 287 (9), 6266-74.
Zhu, W.; Petrashevskaya, N.; Ren, S.; Zhao, A.; Chakir, K.; Gao, E.; Chuprun, J. K.; Wang, Y.; Talan, M.; Dorn, G. W., 2nd; Lakatta, E. G.; Koch, W. J.; Feldman, A. M.; Xiao, R. P., Gi-biased beta2AR signaling links GRK2 upregulation to heart failure, Circ Res, 2012, 110 (2), 265-74.
Gupta, A.; Akki, A.; Wang, Y.; Leppo, M. K.; Chacko, V. P.; Foster, D. B.; Caceres, V.; Shi, S.; Kirk, J. A.; Su, J.; Lai, S.; Paolocci, N.; Steenbergen, C.; Gerstenblith, G.; Weiss, R. G., Creatine kinase-mediated improvement of function in failing mouse hearts provides causal evidence the failing heart is energy starved, J Clin Invest, 2012, 122 (1), 291-302.
Sun, H.; Lu, G.; Ren, S.; Chen, J.; Wang, Y., Catabolism of branched-chain amino acids in heart failure: insights from genetic models, Pediatr Cardiol, 2011, 32 (3), 305-10.
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